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Zen and the Art of Repurposing Drugs

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Once considered a DNA co-purifying annoyance, histone proteins have proven to be an essential component of our genomic makeup. Post-translational modification (PTM) to these proteins not only affect DNA accessibility and expression, but the patterns established considerably extend the information potential of the genetic code and are themselves heritable to subsequent generations. Christian Loch of AVM Biomed delves in to epi-genetics (literally “above” the gene) – the field that works to elucidate this “histone code” and greatly expand our comprehension of our own genomic makeup.

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